Adults: Treatment of peripheral neuropathy due to drug-induced vitamin B deficiency: The dose should be determined by the treating physician on an individual basis. Usually 50 mg to 300 mg pyridoxine hydrochloride (vitamin B6) per day are recommended. (1 tablet Vitamin B6-Hevert Tablets contains 100 mg pyridoxine hydrochloride.) – Treatment of pyridoxine-dependent disorders (primary hyperoxaluria type I, homocystinuria, cystathioninuria, xanthurenic aciduria, hypochromic microcytic anemia caused by vitamin B6 deficiency): The dose should be determined by the treating physician on an individual basis. The general recommendation is 10 mg to 250 mg, in individual cases also up to 600 mg and more pyridoxine hydrochloride (vitamin B6) per day. (1 tablet Vitamin B6-Hevert Tablets contains 100 mg pyridoxine hydrochloride.) − Treatment of pyridoxine-dependent disorders (sideroblastic anemia): The dose should be determined by the treating physician on an individual basis. Doses starting at 200 mg pyridoxine hydrochloride (vitamin B6) per day are usually recommended. (1 tablet Vitamin B6-Hevert Tablets contains 100 mg pyridoxine hydrochloride.) Children − Treatment of peripheral neuropathy due to drug-induced vitamin B deficiency: The dose should be determined by the treating physician on an individual basis. Usually 50 mg to 200 mg pyridoxine hydrochloride (vitamin B6) per day are recommended. (1 tablet Vitamin B6-Hevert Tablets contains 100 mg pyridoxine hydrochloride.) − Maintenance therapy following seizures caused by vitamin B6 deficiency in newborns and infants: The dose should be determined by the treating physician on an individual basis. Usually doses starting of 2 mg to 200 mg pyridoxine hydrochloride (vitamin B6) per day are recommended. The amount needed increases based on age and any comorbidities. (1 tablet Vitamin B6-Hevert Tablets contains 100 mg pyridoxine hydrochloride.) − Treatment of pyridoxine-dependent disorders in children over 1 year of age: The dose should be determined by the treating physician on an individual basis. Usually 10 mg to 250 mg (in babies up to 1 year old: 2 mg to 15 mg) pyridoxine hydrochloride (vitamin B6) per day are recommended. (1 tablet Vitamin B6-Hevert Tablets contains 100 mg pyridoxine hydrochloride.) Please note: For the treatment of simple vitamin B6 deficiency 25 mg pyridoxine hydrochloride (vitamin B6) per day is sufficient.

Vitamin B6-Hevert: Active substance: Vitamin B6. Adults and children: Treatment of peripheral neuropathy (neuritis) secondary to drug-induced vitamin B6 deficiency (e.g., caused by medications with active substances such as isoniazid, D-penicillamine, cycloserine). Maintenance therapy following seizures caused by vitamin B6 deficiency in newborns and infants. Treatment of pyridoxine-dependent disorders in children over 1 year of age (rare metabolic disorders such as primary hyperoxaluria type I, homocystinuria, cystathioninuria, xanthurenic aciduria or rare blood formation disorders such as sideroblastic anemia, hypochromic microcytic anemia caused by vitamin B6 deficiency which can be treated in part with higher vitamin B6 doses). For risks and side effects read the package leaflet and ask your doctor or pharmacist.